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CASE STUDY: OBESE ALCOHOLIC MALE'S 6-MONTH TRANSFORMATION

ZEPBOUND, PEPTIDES, NUTRITION, & EXERCISE INTERVENTION

PATIENT PROFILE

  • Name: John D. (pseudonym)
  • Age: 52
  • Height: 5'10", Weight: 295 lbs, 295 lbs, BMI: 42.3
  • Alcohol Use: 6-8 drinks/day for 10+ years
  • Comorbidities: Pre-diabetes, hypertension, NAFLD, low testosterone
  • Mental Health: Depressive symptoms, poor sleep, low motivation

MEDICAL MANAGEMENT

  • Zepbound (tirzepatide): Started at 2.5 mg,  titrated to 10mg/week
  • Peptides: CJC-1295/Ipamorelin, BPC-157, Tesamorelin
  • Supplements: Vitamin D3, omega-3s, NAC, L-glutamine
  • Hormone Support: Testosterone cypionate 100mg/weel (after detox)

NUTRITIONAL PLAN

  • PHASE 1 (WEEKS 1-8)
  • Modified Mediterranean diet, 1500-1700 kcal/day
  • Alcohol cessation, high hydration, lean proteins, healthy fats 
  • PHASE 2 (WEEKS 9-24)
  • Reintroduce complex cards, card cycling, intermittent fasting

FITNESS PROTOCOL

  • MONTHS 1-2
  • Daily walks, resistance bands, mobility work 
  • MONTHS 3-4
  • Strength training, HIIT cyclying
  • MONTHS 5-6
  • Progressive overload, hikes, sauna & cold plunges

RESULTS AFTER 6 MONTHS

  • Weight: 295 lbs --> 214 lbs
  • BMI: 42.3 --> 30.6
  • A l c: 6.1% --> 5.3%
  • Liver enzymes: Elevated --> Normal
  • Testosterone: 240 --> 720 ng/dL
  • Alcohol Use: Daily --> 100% abstinent 
  • Sleep: Poor --> 7-8 hrs/night
  • Mood: Low --> High motivation

KEYS TO SUCCESS

  • Medical supervision & accountability 
  • Zepbound for appetite and metabolic control
  • Peptides for repair and fat loss
  • Structured, phased nutrition and training
  • Emotional suport and behavioral change

Copyright © 2025 Kenneth Spielvogel, MD - All Rights Reserved.

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